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Том 15 №3 2013 год - Нефрология и диализ

Биомаркеры острого почечного повреждения: клинические аспекты (Обзор литературы)

Колесников С.В. Борисов А.С.

Аннотация: Острое почечное повреждение (ОПП) является распространенным, тяжелым, дорогостоящим в лечении и опасным для жизни состоянием, поражающим критически больных пациентов. В последние десятилетия внимание исследователей приковано к поиску биомаркеров ОПП, способных к раннему и адекватному мониторингу нарушенной функции почек, что необходимо для своевременного начала заместительной почечной терапии и улучшения прогноза. В литературном обзоре изложены результаты применения современных биомаркеров ОПП в клинической практике у различных категорий пациентов с ОПП. Авторами обобщены результаты доказательного использования биомаркеров ОПП на основе современных статистических методов оценки их информативности, представлены данные метаанализа, проанализированы проблемы клинической пригодности маркеров ОПП и перспективы их дальнейшего применения.

Для цитирования: Колесников С.В., Борисов А.С. Биомаркеры острого почечного повреждения: клинические аспекты (Обзор литературы). Нефрология и диализ. 2013. 15(3):184-190. doi:

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Ключевые слова: acute kidney injury, biomarkers, outcomes, острое почечное повреждение, биомаркеры, исходы

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