<< Вернуться к списку статей журнала
Том 19 №3 2017 год - Нефрология и диализ
Современные представления о контраст-индуцированном остром почечном повреждении. Взгляд интервенционного радиолога
Хильчук А.А.
Власенко С.В.
Щербак С.Г.
Сарана А.М.
Бабунашвили А.М.
DOI: 10.28996/1680-4422-2017-3-407-417
Аннотация: Клинически значимое контраст-индуцированное повреждение (КИ-ОПП) является тяжелым осложнением рентген-эндоваскулярных процедур и связана с высокими показателями заболеваемости, смертности и значимыми социо-экономическими потерями. Повреждение почек после выполнения коронароангиографии или чрескожного коронарного вмешательства может развиться в 1-2% случаев общей популяции и у почти 50% пациентов с высоким риском развития КИ-ОПП. Основным и частым фактором, предрасполагающим к развитию контраст-индуцированного острого почечного повреждения, является уже имеющееся снижение почечной функции. Раннее выявление пациентов высокого риска развития КИ-ОПП со сниженной почечной функцией крайне важно для своевременного начала профилактических мер и последующего снижения вероятности повреждения почечной паренхимы с дальнейшим ухудшением почечной функции. Быстрая или почти мгновенная реакция некоторых биологических маркеров на субклиническое острое почечное повреждение помогает в диагностике нефропатии и на сегодняшний день является перспективным направлением исследования. Несмотря на небольшое количество имеющихся различий в рекомендациях, существует несколько строгих позиций в профилактике и лечении контраст-индуцированной нефропатии. Внутривенная нагрузка 0,9% раствором NaCl является единственной доказанной эффективной мерой профилактики КИ-ОПП, в то время как иная фармакологическая поддержка требует дальнейшего изучения и проведения большего количества проспективных исследований. Данная статья посвящена обзору современной литературы, посвященной причинам, профилактике и лечению КИ-ОПП с позиции доказательной медицины.
Для цитирования: Хильчук А.А., Власенко С.В., Щербак С.Г., Сарана А.М., Бабунашвили А.М. Современные представления о контраст-индуцированном остром почечном повреждении. Взгляд интервенционного радиолога. Нефрология и диализ. 2017. 19(3):407-417. doi: 10.28996/1680-4422-2017-3-407-417
Весь текст
Ключевые слова: нефропатия,
повреждение почек,
контрастные вещества,
биомаркеры почечного повреждения,
nephropathy,
renal damage,
contrast media,
renal damage biomarkersСписок литературы:- Almeida Mendes C. de и др. Carbon Dioxide as Contrast Medium to Guide Endovascular Aortic Aneurysm Repair. Annals of Vascular Surgery. 2017. 39. C. 67-73.
- Andreucci M. и др. Acute Kidney Injury by Radiographic Contrast Media : Pathogenesis and Prevention 2014.
- Ashalatha V.L. и др. Biomarker response to contrast administration in diabetic and nondiabetic patients following coronary angiography. Indian journal of nephrology. 2017. № 1 (27). C. 20-27.
- Aspelin P. и др. Nephrotoxic Effects in High-Risk Patients Undergoing Angiography. New England Journal of Medicine. 2009. № 6 (348). C. 2301-2303.
- Bachorzewska-Gajewska H. и др. Could Neutrophil-Gelatinase-Associated Lipocalin and Cystatin C Predict the Development of Contrast-Induced Nephropathy after Percutaneous Coronary Interventions in Patients with Stable Angina and Normal Serum Creatinine Values? Kidney and Blood Pressure Research. 2007. № 6 (30). C. 408-415.
- Bagshaw S.M., Culleton B.F. Contrast-induced nephropathy: Epidemiology and prevention. Minerva Cardioangiologica. 2006. Т. 54. № 1. 109-129 с.
- Bartels E.D. и др. Acute anuria following intravenous pyelography in a patient with myelomatosis. Acta medica Scandinavica. 1954. № 4 (150). C. 297-302.
- Bartholomew B.A. и др. Impact of nephropathy after percutaneous coronary intervention and a method for risk stratification. American Journal of Cardiology. 2004. № 12 (93). C. 1515-1519.
- Bonventre J. V. Kidney Injury Molecule-1 (KIM-1): A specific and sensitive biomarker of kidney injury. Scandinavian Journal of Clinical and Laboratory Investigation. 2008. № sup241 (68). C. 78-83.
- Brady H.R., Singer G.G. Acute Renal Failure. Lancet (London, England). 1995. № 8989 (346). C. 1448-1460.
- Brar S.S. и др. Sodium Bicarbonate vs Sodium Chloride for the Prevention of Contrast Undergoing Coronary Angiography. JAMA : the journal of the American Medical Association. 2008. № 9 (300). C. 1038-1046.
- Brezis M R.S. Hypoxia of the Renal Medulla - Its Implications for Disease. N Engl J Med. 1995. № 10 (332). C. 647-655.
- Briguori C. и др. RenalGuard system in high-risk patients for contrast-induced acute kidney injury. American Heart Journal. 2016. (173). C. 67-76.
- Bryant B.J., Im K., Broome D.R. Evaluation of the incidence of nephrogenic systemic fibrosis in patients with moderate renal insufficiency administered gadobenate dimeglumine for MRI. Clinical Radiology. 2009. № 7 (64). C. 706-713.
- Busch S.V.E. и др. Prevention of contrast-induced nephropathy in STEMI patients undergoing primary percutaneous coronary intervention: A systematic review. Journal of Interventional Cardiology. 2013. № 1 (26). C. 97-105.
- Caixeta A., Nikolsky E., Mehran R. Prevention and treatment of contrast-associated nephropathy in interventional cardiology. Current cardiology reports. 2009. № 5 (11). C. 377-83.
- Caridi J.G. Vascular Imaging with Carbon Dioxide: Confidence in a Safe, Efficacious, User-Friendly System. Seminars in interventional radiology. 2015. № 4 (32). C. 339-42.
- Chang C.-F., Lin C.-C. Current concepts of contrast-induced nephropathy: A brief review. Journal of the Chinese Medical Association. 2013. № 12 (76). C. 673-681.
- Choi M.-J. и др. The prevention of contrast-induced nephropathy by simultaneous hemofiltration during coronary angiographic procedures: A comparison with periprocedural hemofiltration. International Journal of Cardiology. 2014. № 3 (176). C. 941-945.
- Cigarroa R.G. и др. Dosing of contrast material to prevent contrast nephropathy in patients with renal disease. The American journal of medicine. 1989. № 6 Pt 1 (86). C. 649-52.
- Cooper M.W., Reed P.J. Comparison of ionic and non-ionic contrast agents in cardiac catheterization: the effects of ventriculography and coronary arteriography on hemodynamics, electrocardiography, and serum creatinine. Catheterization and cardiovascular diagnosis. 1991. № 4 (22). C. 267-77.
- Cubero-Gómez J.M. и др. Severe thrombocytopenia induced by iodinated contrast after coronary angiography: The use of gadolinium contrast and intravascular ultrasound as an alternative to guide percutaneous coronary intervention. Revista Portuguesa de Cardiologia. 2017. № 1 (36). C. 61.e1-61.e4.
- Dong Y. и др. How Strong Is the Evidence for Sodium Bicarbonate to Prevent Contrast-Induced Acute Kidney Injury After Coronary Angiography and Percutaneous Coronary Intervention?. Medicine. 2016. № 7 (95). C. e2715.
- Duan S.-B. и др. Urinary KIM-1, IL-18 and Cys-c as early predictive biomarkers in gadolinium-based contrast-induced nephropathy in the elderly patients. Clinical Nephrology. 2013. № 11 (80). C. 349-354.
- El-Ashmawy N.E. и др. Kidney injury molecule-1 (Kim-1): an early biomarker for nephropathy in type II diabetic patients. International Journal of Diabetes in Developing Countries. 2015. (35). C. 431-438.
- Filiopoulos V. и др. Plasma neutrophil gelatinase-associated lipocalin (NGAL) as an early predictive marker of contrast-induced nephropathy in hospitalized patients undergoing computed tomography. Clinical Kidney Journal. 2013. № 6 (6). C. 578-583.
- Filiopoulos V., Biblaki D., Vlassopoulos D. Neutrophil gelatinase-associated lipocalin (NGAL): a promising biomarker of contrast-induced nephropathy after computed tomography. Renal Failure. 2014. № 6 (36). C. 979-986.
- Finn W.F. The clinical and renal consequences of contrast-induced nephropathy. Nephrology Dialysis Transplantation. 2006. № Supplement 1 (21). C. i2-i10.
- Gernot Schilcher, Werner Ribitsch, Ronald Otto, et al. Early detection and intervention using neutrophil gelatinase-associated lipocalin (NGAL) may improve renal outcome of acute contrast media induced nephropathy: A randomized controlled trial in patients undergoing intra-arterial angiography. BMC Nephrol. 2011.
- Guan X. и др. Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells. DNA and Cell Biology. 2017. № 1 (36). C. 67-76.
- Han W.K. и др. Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury. Kidney International. 2002. № 1 (62). C. 237-244.
- Haschek E L.O. A contribution to the practical use of photography according to Roentgen. Wien Chir Wochenschr. 1896. № 9. C. 63.
- He A. и др. Nephrogenic systemic fibrosis: fibrotic plaques and contracture following exposure to gadolinium-based contrast media. BMJ case reports. 2016. C. bcr2016214927.
- Hörl W.H. Contrast induced nephropathy. Wiener klinische Wochenschrift. 2009. № 1-2 (121). C. 15-32.
- Hou S.H. и др. Hospital-acquired renal insufficiency: a prospective study. The American journal of medicine. 1983. № 2 (74). C. 243-8.
- Jo S.-H. и др. Renal toxicity evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in patients with renal insufficiency undergoing coronary angiography: the RECOVER study: a randomized controlled trial. Journal of the American College of Cardiology. 2006. № 5 (48). C. 924-30.
- Kalyesubula R., Bagasha P., Perazella M.A. ACE-I / ARB Therapy prior to Contrast Exposure : What Should the Clinician Do? 2014.
- Kellum J.A. и др. Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified delphi process. Clinical Journal of the American Society of Nephrology. 2008. № 3 (3). C. 887-894.
- Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron - Clinical Practice. 2012. № 4 (120). C. 179-184.
- Killmann S.A., Gjorup S., Thaysen J.H. Fatal acute renal failure following intravenous pyelography in a patient with multiple myeloma. Acta medica Scandinavica. 1957. № 1 (158). C. 43-6.
- Lichosik M. и др. Interleukin 18 and neutrophil-gelatinase associated lipocalin in assessment of the risk of contrast-induced nephropathy in children. Central European Journal of Immunology. 2015. № 4 (40). C. 447-453.
- Loughlin K.R., Hawtrey C.E. Moses Swick, the father of intravenous urography. Urology. 2003. № 2 (62). C. 385-9.
- Maioli M. и др. Sodium Bicarbonate Versus Saline for the Prevention of Contrast-Induced Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention. Journal of the American College of Cardiology. 2008. № 8 (52). C. 599-604.
- Maioli M. и др. Preprocedural score for risk of contrast-induced nephropathy in elective coronary angiography and intervention. Journal of cardiovascular medicine (Hagerstown, Md.). 2010. № 6 (11). C. 444-9.
- Malyszko J. и др. Urinary and Serum Biomarkers after Cardiac Catheterization in Diabetic Patients with Stable Angina and without Severe Chronic Kidney Disease. Renal Failure. 2009. № 10 (31). C. 910-919.
- Mawad H. и др. Changes in urinary and serum levels of novel biomarkers after administration of gadolinium-based contrast agents. Biomarker Insights. 2016. (11). C. 91-94.
- McCullough P.A. и др. Risk Prediction of Contrast-Induced Nephropathy. The American Journal of Cardiology. 2006. № 6 (98). C. 27-36.
- McCullough P.A. Contrast-Induced Acute Kidney Injury. Journal of the American College of Cardiology. 2008. № 15 (51). C. 1419-1428.
- McCullough P.A. и др. Contrast-Induced Acute Kidney Injury. Journal of the American College of Cardiology. 2016. № 13 (68). C. 1465-1473.
- McCullough P.A., Sandberg K.R. Epidemiology of contrast-induced nephropathy. Reviews in cardiovascular medicine. 2003. (4 Suppl 5). C. S3-9.
- Mehran R. и др. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: Development and initial validation. Journal of the American College of Cardiology. 2004. № 7 (44). C. 1393-1399.
- Mehran R. и др. Ionic Low-Osmolar Versus Nonionic Iso-Osmolar Contrast Media to Obviate Worsening Nephropathy After Angioplasty in Chronic Renal Failure Patients. JACC: Cardiovascular Interventions. 2009. № 5 (2). C. 415-421.
- Mehran R., Nikolsky E. Contrast-induced nephropathy: definition, epidemiology, and patients at risk. Kidney international. Supplement. 2006. № 100 (69). C. S11-S15.
- Michaely H.J. и др. Gadobutrol in Renally Impaired Patients. Investigative Radiology. 2017. № 1 (52). C. 55-60.
- Morcos S.K., Thomsen H.S., Webb J.A. Contrast-media-induced nephrotoxicity: a consensus report. Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR). European radiology. 1999. № 8 (9). C. 1602-13.
- Nash K., Hafeez A., Hou S. Hospital-acquired renal insufficiency. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2002. № 5 (39). C. 930-6.
- Osborne E.D. и др. Landmark article Feb 10, 1923: Roentgenography of urinary tract during excretion of sodium iodid. By Earl D. Osborne, Charles G. Sutherland, Albert J. Scholl, Jr. and Leonard G. Rowntree. JAMA. 1983. № 20 (250). C. 2848-53.
- Ozawa Y. и др. Effects of Gadodiamide on cell proliferation and collagen production in cultured human dermal fibroblasts. Archives of Dermatological Research. 2016. № 10 (308). C. 695-701.
- Parfrey P. The clinical epidemiology of contrast-induced nephropathy. Cardiovasc Intervent Radiol. 2005. (28 Suppl 2). C. S3-11.
- Pianta T.J. и др. Monitoring Treatment of Acute Kidney Injury with Damage Biomarkers. Toxicology Letters. 2017.
- Rear R., Bell R.M., Hausenloy D.J. Education in Heart Contrast-induced nephropathy following angiography and cardiac interventions. Heart. 2016. C. 638-648.
- Renton M. и др. The use of carbon dioxide angiography for renal sympathetic denervation: a technical report. The British Journal of Radiology. 2016. № 1068 (89). C. 20160311.
- Rey J.R. и др. Prevention of contrast-induced nephropathy with haemofiltration in high-risk patients after percutaneous coronary intervention. Acute Cardiac Care. 2011. № 3 (13). C. 164-169.
- Ribichini F. и др. Early creatinine shifts predict contrast-induced nephropathy and persistent renal damage after angiography. American Journal of Medicine. 2010. № 8 (123). C. 755-763.
- Ribichini F. и др. Comparison of serum creatinine and cystatin C for early diagnosis of contrast-induced nephropathy after coronary angiography and interventions. Clinical Chemistry. 2012. № 2 (58). C. 458-464.
- Ribitsch W. и др. Neutrophil gelatinase-associated lipocalin (NGAL) fails as an early predictor of contrast induced nephropathy in chronic kidney disease (ANTI-CI-AKI study). Scientific reports. 2017. (7). C. 41300.
- Rittenhouse D.R. и др. Contrast media use in patients with chronic kidney disease undergoing coronary angiography: A systematic review and meta-analysis of randomized trials. New England Journal of Medicine. 2017. № 6 (228). C. 137-144.
- Rudnick M.R. и др. Contrast media-associated nephrotoxicity. Seminars in nephrology. 1997. № 1 (17). C. 15-26.
- Sarabu N., Rahman M. Nephrology Update: Acute Kidney Injury. FP essentials. 2016. (444). C. 11-7.
- Sendeski M.M. Pathophysiology of renal tissue damage by iodinated contrast media. Clinical and Experimental Pharmacology and Physiology. 2011. № 5 (38). C. 292-299.
- Sendeski M.M. и др. Iodinated contrast media cause endothelial damage leading to vasoconstriction of human and rat vasa recta. AJP: Renal Physiology. 2012. C. 1592-1598.
- Solomon R.J. и др. Contrast-induced nephropathy and long-term adverse events: Cause and effect?. Clinical Journal of the American Society of Nephrology. 2009. № 7 (4). C. 1162-1169.
- Soulez G. и др. Prospective Cohort Study of Nephrogenic Systemic Fibrosis in Patients With Stage 3-5 Chronic Kidney Disease Undergoing MRI With Injected Gadobenate Dimeglumine or Gadoteridol. American Journal of Roentgenology. 2015. № 3 (205). C. 469-478.
- Spini V. и др. Effects of two different treatments with continuous renal replacement therapy in patients with chronic renal dysfunction submitted to coronary invasive procedures. The Journal of invasive cardiology. 2013. № 2 (25). C. 80-4.
- Sudarsky D., Nikolsky E. Contrast-induced nephropathy in interventional cardiology. International Journal of Nephrology and Renovascular Disease. 2011. (4). C. 85-99.
- Tamai N. и др. Sodium bicarbonate for the prevention of contrast-induced nephropathy: the efficacy of high concentration solution. The Journal of invasive cardiology. 2012. № 9 (24). C. 439-42.
- Tepel M. и др. Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. The New England journal of medicine. 2000. № 3 (343). C. 180-4.
- Timmeren M.M. van и др. Tubular kidney injury molecule-1 (KIM-1) in human renal disease Journal of Pathology. 2007. № 2 (212). C. 209-217.
- Tziakas D. и др. Development of an easily applicable risk score model for contrast-induced nephropathy prediction after percutaneous coronary intervention: A novel approach tailored to current practice. International Journal of Cardiology. 2013. № 1 (163). C. 46-55.
- Victor S.M. и др. Risk scoring system to predict contrast induced nephropathy following percutaneous coronary intervention. Indian Heart Journal. 2014. № 5 (66). C. 517-524.
- Waikar S.S., Bonventre J.V. Creatinine kinetics and the definition of acute kidney injury. Journal of the American Society of Nephrology : JASN. 2009. (20). C. 672-679.
- Wang N. и др. The effect of N-acetylcysteine on the incidence of contrast-induced kidney injury: A systematic review and trial sequential analysis. International Journal of Cardiology. 2016. (209). C. 319-327.
- Weisbord S.D. и др. Associations of Increases in Serum Creatinine with Mortality and Length of Hospital Stay after Coronary Angiography. Journal of American Society of Nephrology. 2006. (17). C. 2871-2877.
- Weisz G. и др. Safety and Performance of Targeted Renal Therapy: The Be-RITe! Registry. Journal of Endovascular Therapy. 2009. № 1 (16). C. 1-12.
- Wu Y.W. и др. Prevention and Management of Adverse Reactions Induced by Iodinated Contrast Media. Annals of the Academy of Medicine, Singapore. 2016. № 4 (45). C. 157-64.
- You W. и др. The value of urinary neutrophil gelatinase-associated lipocalin for early diagnosis of contrast-induced nephropathy]. Zhonghua xin xue guan bing za zhi. 2016. № 12 (44). C. 1024-1029.
- Zhao X. и др. Kidney Injury Molecule-1 Enhances Endocytosis of Albumin in Renal Proximal Tubular Cells. Journal of Cellular Physiology. 2016. № 4 (231). C. 896-907.
Другие статьи по теме