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Том 16 №2 2014 год - Нефрология и диализ

Клинико-генетическая гетерогенность cтероид-резистентного нефротического синдрома у детей (Обзор литературы)

Приходина Л.С.

Аннотация: В обзоре представлены современные литературные сведения о клинико-генетической гетерогенности стероид-резистентного нефротического синдрома у детей, как спорадических случаев, так и в составе ряда наследственных синдромов с характерными экстраренальными проявлениями. Обращается внимание на различный спектр генов, ассоциированных со стероид-резистентным нефротическим синдромом в зависимости от возраста манифестации заболевания, семейного характера патологии, морфологических вариантов и наличия характерных экстраренальных проявлений. Освещаются генотип-фенотипические ассоциации и потенциальная взаимосвязь с эффективностью иммуносупрессивной терапии стероид-резистентного нефротического синдрома в детском возрасте.

Для цитирования: Приходина Л.С. Клинико-генетическая гетерогенность cтероид-резистентного нефротического синдрома у детей (Обзор литературы). Нефрология и диализ. 2014. 16(2):236-254. doi:

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Ключевые слова: дети, стероид-резистентный нефротический синдром, гены, наследственные синдромы, children, steroid-resistant nephrotic syndrome, genes, inherited syndromes

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